What is MAT (Medication Assisted Treatment) in 2025

What Is MAT?

MAT or Medication assisted treatment is used primarily for opioid and alcohol use disorders. The idea is simple: medications help stabilize brain chemistry while therapy and support systems address the psychological and behavioral sides of addiction. When used correctly, MAT improves treatment retention, reduces the risk of overdose, and increases the chances of long-term sobriety.

Despite its effectiveness, MAT is sometimes misunderstood. Some people believe using medication to treat addiction is just “trading one addiction for another.” But that’s not true. MAT medications are carefully managed by healthcare professionals and are designed to help people regain control of their lives, not get high.

Medications Used in MAT

Suboxone

Suboxone is one of the most well-known medications for opioid addiction. It contains buprenorphine and naloxone. Buprenorphine is a partial opioid agonist, meaning it binds to opioid receptors in the brain but only partially activates them. This helps reduce cravings and withdrawal symptoms without producing the same high as drugs like heroin or fentanyl. Naloxone is included to prevent misuse—if someone tries to inject Suboxone, the naloxone triggers withdrawal symptoms.

Suboxone is typically taken as a sublingual film or tablet and is prescribed in outpatient settings, making it accessible for many people in recovery.

Sublocade

Sublocade is an extended-release version of buprenorphine, administered as a monthly injection. One of the biggest benefits of Sublocade is that it removes the need to take daily medication. This can help prevent missed doses and reduce the temptation to misuse medication.

For people who struggle with taking medication consistently or who want a more discreet treatment option, Sublocade can be a great choice.

Naltrexone (Vivitrol)

Naltrexone is used to treat both opioid and alcohol addiction. Unlike Suboxone and Sublocade, which contain buprenorphine, naltrexone is an opioid antagonist. It completely blocks the effects of opioids, meaning if someone tries to use heroin or other opioids, they won’t feel the high. This makes relapse less appealing.

Naltrexone is also used for alcohol use disorder by reducing cravings and the pleasurable effects of drinking. It’s available in a daily pill form or as a monthly injection called Vivitrol.

Campral (Acamprosate)

Campral is specifically for alcohol addiction. It helps restore balance in the brain’s neurotransmitters, reducing cravings and the distress some people feel when they stop drinking. Unlike naltrexone, which blocks the pleasurable effects of alcohol, Campral helps manage withdrawal symptoms and long-term cravings. It’s taken as a daily pill and works best when combined with therapy and support groups.

Benefits of MAT (Medication Assisted Treatment)

1. Reduces Cravings and Withdrawal Symptoms – Medications like Suboxone and Campral make early recovery more manageable by minimizing withdrawal discomfort.
2. Decreases Overdose Risk – People taking MAT have a lower risk of relapse, which means they’re less likely to experience a fatal overdose.
3. Improves Treatment Retention – Studies show that people who use MAT are more likely to stay in treatment and achieve long-term recovery.
4. Supports Mental Health – Many people with addiction also have co-occurring mental health disorders. MAT helps stabilize mood and brain function, allowing them to engage in therapy more effectively.
5. Promotes a Normal Lifestyle – By reducing cravings and withdrawal symptoms, MAT allows people to focus on work, family, and personal growth without being consumed by addiction.

Common Misconceptions About MAT

“It’s Just Replacing One Drug with Another”

MAT is about managing addiction, not substituting one substance for another. The medications used in MAT don’t produce a high when taken as prescribed, and they help people function normally.

“You’re Not Really Sober If You’re on MAT”

Recovery looks different for everyone. Some people achieve sobriety through abstinence-based methods, while others need medication support. Being in recovery isn’t about following a one-size-fits-all rule—it’s about finding what works.

“You Have to Be on MAT Forever”

Some people use MAT long-term, while others taper off over time. The length of treatment depends on individual needs. Research shows that staying on MAT for at least a year increases the chances of long-term recovery.

Is MAT Right for You?

MAT isn’t for everyone, but it’s a great option for people who struggle with severe cravings and relapse. If you’re considering MAT, talk to a healthcare provider about your options. They’ll assess your medical history, substance use patterns, and personal goals to help determine the best treatment plan for you.

Combining MAT with Therapy and Support

MAT works best when combined with counseling and behavioral therapies. Addiction isn’t just a physical condition—it’s also deeply rooted in emotions, behaviors, and past trauma. Therapy helps address these issues, and support groups like NA, AA, or SMART Recovery can provide additional motivation and community.

Conclusion

Medication-assisted treatment has changed the way we approach addiction recovery. With medications like Suboxone, Sublocade, naltrexone, and Campral, people struggling with opioid and alcohol addiction have more tools to help them stay sober. MAT isn’t a magic cure, but it’s a highly effective strategy for reducing cravings, preventing relapse, and improving quality of life.

If you or a loved one is considering MAT, reach out to a treatment provider to discuss your options. Recovery is possible, and MAT can be a powerful step in the right direction.