Abstinence The practice of not engaging in a particular behavior, specifically the use of psychoactive substances. Synonyms: SobrietyRelated Articles: Partial Hospitalization Program for Opioid AddictionNature Immersion Therapy for Meth Addiction5 Facts About the Opioid EpidemicIs My Loved One Abusing Adderall?5 Ways to Prevent a Heroin Relapse